CDR2 Antibody [PE/Atto594]

Product Discontinued

CDR2 Antibody [PE/Atto594] Summary

• Immunogen: A synthetic peptide made to a C-terminal region of human CDR2 [Swiss-Prot# Q01850]
• Localization: Cytoplasmic and Nuclear
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CDR2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: rat (85%).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for CDR2 Antibody [PE/Atto594]

• CDR62
• cerebellar degeneration-related protein (62kD)
• cerebellar degeneration-related protein 2
• cerebellar degeneration-related protein 2, 62kDa
• Major Yo paraneoplastic antigen
• Paraneoplastic cerebellar degeneration-associated antigen
• PCD17
• Yo paraneoplastic antigen
• Yo

Background

CDR2 suppresses the transcriptional activity and DNA binding of nuclear factor-kappa B by an unknown mechanism. The neuron specific expression of CDR-2 is regulated by a post-transcriptional mechanism. CDR2 antibodies are useful tools for transcription regulation and neurology.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for CDR2 Antibody (NB110-58345PEATT594). (Showing 1 - 1 of 1 FAQ).

1. I'm looking for an antibody against human CDR2 to recognize thymic epithelial cells. You have several anti CDR2 antibodies. Are they against a thymic epithelial antigen or against the cerebellar degeneration-related protein 2, 62kDa?
   • Yes, the specific antibody you have inquired about is against cerebellar degeneration-related protein 2, 62 kDa. Moreover, all of our CDR2 primaries are against the same target.

Bioinformatics

• Gene Symbol: CDR2