CD97 Antibody

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Immunohistochemistry-Paraffin: CD97 Antibody [NLS2651] - Analysis of anti-CD97 antibody with human colon.

Product Details

Summary
Reactivity Hu, MkSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

CD97 Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human CD97.
Specificity
Human CD97. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Monkey (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CD97
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 2 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Marmoset (88%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CD97 Antibody

  • CD97 antigenseven-span transmembrane protein
  • CD97 molecule
  • Leukocyte antigen CD97
  • seven transmembrane helix receptor
  • seven-transmembrane, heterodimeric receptor associated with inflammation
  • TM7LN1

Background

CD97, a CD55 Receptor, is a leukocyte antigen located on most activated leukocytes. CD97 is highly homologous to EMR2 with five EGF-like domains in the N-terminal extracellular domain, suggesting that it may be involved in cell signaling as well as in cell adhesion (Hamann et al., 1996). Two variants are produced by alternative splicing, where the shorter form lacks exons 5 and 6 and reduces the number of EGF-like domains from 5 to 3, compared to the full-length isoform. CD97 is associated with with the activated lesions of multiple sclerosis. CD97 expression is also implicated in the dedifferentiation of colon and thyroid tumors. CD97 is expressed abundantly in cells of hematopoietic origin and is markedly upregulated on activated T and B cells. ESTs have been isolated from a wide variety of tissue libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CD97
Entrez