CD97 Antibody (3B11)

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Western Blot: CD97 Antibody (3B11) [H00000976-M13] - Detection against Immunogen (107.36 KDa).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
3B11
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

CD97 Antibody (3B11) Summary

Immunogen
CD97 (AAH26690, 1 a.a. - 742 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGRHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CD97
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Application Notes
It has been used for ELISA and WB.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CD97 Antibody (3B11)

  • CD97 antigenseven-span transmembrane protein
  • CD97 molecule
  • Leukocyte antigen CD97
  • seven transmembrane helix receptor
  • seven-transmembrane, heterodimeric receptor associated with inflammation
  • TM7LN1

Background

CD97 antigen is a receptor involved in both adhesion and signaling processes early after leukocyte activation. It also plays an essential role in leukocyte migration. The unprocessed precursor is 853 amino acids long and has a predicted molecular weight of 91.9KDa. CD97 antigen is a heterodimer consisting of a large extracellular alpha subunit and a seven-transmembrane beta subunit that are non-covalently linked. It contains five EGF-like domains and one GPS domain. This protein interacts with complement decay-accelerating factor (DAF) through the first two EGF domains, and with chondroitin sulfate (only isoform 1) through the fourth EGF domain. CD97 antigen is broadly expressed and it is present on most hematopoietic cells. It is also abundantly expressed by smooth muscle cells. Expression of this protein is increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients of rheumatoid arthritis. This protein is rapidly up-regulated during lymphocyte activation. C97 antigen belongs to the G-protein coupled receptor 2 fmaily and the LN-TM7 subfamily.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CD97
Uniprot