CD79B Antibody [mFluor Violet 500 SE] - (Research Grade polatuzumab Biosimilar)

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clonality: Monoclonal
• Host: Human
• Conjugate: mFluor Violet 500 SE

CD79B Antibody [mFluor Violet 500 SE] - (Research Grade polatuzumab Biosimilar) Summary

• Description: The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
  
  Also known as 'polatuzumab'.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: CD79b
• Source: CHO
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: CD79B
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted species reactivity: Mouse, Rat, Pig, Macaque, Cynomolgus

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD79B Antibody [mFluor Violet 500 SE] - (Research Grade polatuzumab Biosimilar)

• B29
• B29B-cell-specific glycoprotein B29
• B-cell antigen receptor complex-associated protein beta chain
• CD79B antigen (immunoglobulin-associated beta)
• CD79b antigen
• CD79b molecule, immunoglobulin-associated beta
• CD79B
• IGB
• IGBAGM6
• Ig-beta
• Immunoglobulin-associated B29 protein

Background

Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79alpha/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (1)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD79B