CD79B Antibody (HM79-11) [FITC]

Flow Cytometry: CD79B Antibody (HM79-11) [FITC] [NB100-64017] - Staining of mouse spleen cells with HAMSTER ANTI MOUSE CD79b:FITC

• Reactivity: Mu
• Applications: Flow
• Clone: HM79-11
• Clonality: Monoclonal
• Host: Armenian Hamster
• Conjugate: FITC
• Concentration: 0.1 mg/ml

CD79B Antibody (HM79-11) [FITC] Summary

• Immunogen: CD79 alpha/CD79 beta heterodimer purified from WEHI-231 B cells
• Specificity: NB100-65611 recognizes murine CD79 beta, which is expressed by B cells as part of the B cell receptor complex (immunoglobulin and the CD79 alpha/beta heterodimer). Murine CD79 beta is expressed at the cell surface of pro-B cells prior to surface immunoglobulin, and is expressed throughout B cell differentiation. CD79 beta is a B cell specific marker, valuable for the detection of B cells at all maturation stages.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Armenian Hamster
• Gene: CD79B
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry Neat

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% Bovine Serum Albumin
• Preservative: 0.09% Sodium Azide
• Concentration: 0.1 mg/ml
• Purity: Protein G purified

Alternate Names for CD79B Antibody (HM79-11) [FITC]

• B29
• B29B-cell-specific glycoprotein B29
• B-cell antigen receptor complex-associated protein beta chain
• CD79B antigen (immunoglobulin-associated beta)
• CD79b antigen
• CD79b molecule, immunoglobulin-associated beta
• CD79B
• IGB
• IGBAGM6
• Ig-beta
• Immunoglobulin-associated B29 protein

Background

CD79b is the B cell antigen receptor Ig beta chain (BCR Ig beta), which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg). The mIgM component binds antigen and the Ig alpha/Ig beta heterodimer tranduces signals. CD79 beta is a B cell specific marker, valuable for the detection of B cells at all maturation stages.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD79B Antibody (NB100-64017)(1)

Publication using NB100-64017

• Mariko Koyama, Katsuhiko Ishihara, Hajime Karasuyama et al. CD79a/CD79b heterodimers are expressed on pro-B cell surfaces without associated m heavy chain International Immunology 1997-11-01 [PMID: 9418137]
  
  Details:
  This citation used the FITC version of this antibody.

Bioinformatics

• Gene Symbol: CD79B
• Uniprot:
  • P15530(Mouse)