CCT5 Antibody (PK/29/23/8d)

Product Discontinued

CCT5 Antibody (PK/29/23/8d) Summary

• Immunogen: CCT5 chaperonin molecule complex.
• Localization: Cytoplasmic
• Specificity: Recognises the epsilon polypeptide of the CCT5 chaperonin molecule complex. The intact CCT5 complex is composed of eight polypeptides in a double-ring structure. CCT5 is important within cells in aiding the folding of proteins including actin, tubulin and the VHL tumour suppressor protein.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: CCT5
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Gel Super Shift Assays 1:1-1:100
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:250-1:500

Reactivity Notes

Cross reacts with Mouse, Rabbit, Rat, Human and Bovine.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Phosphate buffered saline
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Notes

This product should be stored undiluted.

Alternate Names for CCT5 Antibody (PK/29/23/8d)

• chaperonin containing TCP1, subunit 5 (epsilon)
• epsilon subunit

Background

CCT5 is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCT5
• Entrez:
  • 22948(Human)
  • 21454(Mouse)
  • 24818(Rat)
• Uniprot:
  • P48643(Human)