Casein Kinase 1 gamma Antibody (OTI4D9) [HRP]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI4D9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

Casein Kinase 1 gamma Antibody (OTI4D9) [HRP] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 163-422 of human Casein Kinase 1 gamma (NP_071331) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CSNK1G1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for Casein Kinase 1 gamma Antibody (OTI4D9) [HRP]

• Casein Kinase 1 gamma
• casein kinase 1, gamma 1
• casein kinase I isoform gamma-1
• CKI-gamma 1
• CSNK1G1
• EC 2.7.11
• EC 2.7.11.1

Background

Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIalpha, gamma, episilon and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2beta2 or an alphaalpha'beta2 structure. The alpha catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CSNK1G1