Casein Kinase 1 gamma Products

Description

Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIalpha, gamma, episilon and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2beta2 or an alphaalpha'beta2 structure. The alpha catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.

Bioinformatics

Entrez	214897 Mouse 53944 Human 64086 Rat
Uniprot	AAH17236 Human NP_071331 Human Q9HCP0 Human
Product By Gene ID	53944
Alternate Names	casein kinase 1, gamma 1 casein kinase I isoform gamma-1 CKI-gamma 1 EC 2.7.11 EC 2.7.11.1

Research Areas for Casein Kinase 1 gamma

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Protein Kinase