Calsenilin Antibody

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Western Blot: Calsenilin Antibody [NBP2-16018] - Western Blot analysis of KCNIP3 expression in transfected 293T cell line by KCNIP3 polyclonal antibody. A: Non-transfected lysate. B: KCNIP3 transfected lysate. 12% SDS ...read more
Western Blot: Calsenilin Antibody [NBP2-16018] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 12% SDS PAGE gel, diluted at 1:1000.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.88 mg/ml

Order Details

Calsenilin Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human CSEN. The exact sequence is proprietary.
Localization
Cytoplasm; Cell membrane; Lipid-anchor; Endoplasmic reticulum; Golgi apparatus; Nucleus
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KCNIP3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.88 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Calsenilin Antibody

  • calsenilin
  • calsenilin, presenilin-binding protein, EF hand transcription factor
  • CSEN MGC18289
  • DREAM
  • DREAMA-type potassium channel modulatory protein 3
  • KCHIP3 DRE-antagonist modulator
  • KChIP3
  • Kv channel interacting protein 3, calsenilin
  • Kv channel-interacting protein 3
  • potassium channel interacting protein 3

Background

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KCNIP3
Uniprot