CACNB3 Antibody (7D1) - Azide and BSA Free

Western Blot: CACNB3 Antibody (7D1) [NBP3-13514] - CACNB3 antibody detects CACNB3 protein by western blot analysis. Non-transfected (-) and CACNB3-transfected (+, ) 293T whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with CACNB3 antibody (NBP3-13514) at a dilution of 1:1000.

Immunocytochemistry/Immunofluorescence: CACNB3 Antibody (7D1) [NBP3-13514] - FACS analysis of cos1 cells tranfected with CACNB3 using NBP3-13514 CACNB3 antibody [7D1].

Flow Cytometry: CACNB3 Antibody (7D1) [NBP3-13514] - FACS analysis of cos1 cells tranfected with CACNB3 using NBP3-13514 CACNB3 antibody [7D1].

Western Blot: CACNB3 Antibody (7D1) [NBP3-13514] - WB analysis of cos1 cell transfected with CACNB3 using NBP3-13514 CACNB3 antibody [7D1]. + : Transfected - : Endogenous

• Reactivity: Hu, Pm
• Applications: WB, Flow, ICC/IF
• Clone: 7D1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

CACNB3 Antibody (7D1) - Azide and BSA Free Summary

• Description: Centrifuge briefly prior to opening.
• Immunogen: The immunogen used to generate this antibody corresponds to human CACNB3
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CACNB3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein G purified

Alternate Names for CACNB3 Antibody (7D1) - Azide and BSA Free

• CAB3
• CACNLB3
• Calcium channel voltage-dependent subunit beta 3
• calcium channel, voltage-dependent, beta 3 subunit
• voltage-dependent L-type calcium channel subunit beta-3

Background

The CACNB3 gene encodes for a proteins that are long voltage dependent L-type calcium channel subunit beta-3 gene that aids in regulating surface expression, calcium transport, regulation of transcription factors, and gating of calcium channels. Isoform 3A is 484 amino acids in length with a mass of around 54 kDA while isoform 3B is 447 amino acids long at around 50 kDA. Increasingly, research has investigated the role of the CACNB3 gene in various diseases such as neuronitis, neuropathy, canavan disease, and lambert-eaton myasthenic syndrome. This gene plays a role in many pathways such as CREB transcription, the Celecoxib pathway, MAPK signaling pathway, and the Myometrial Relaxation and Contraction pathways and is known to interact with various other genes such as: CACNA1C, CACNA1B, SYT1, FASLG, and YWHAB.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CACNB3