BST2 Antibody (120G8.04) - Bulk Size

Immunocytochemistry/Immunofluorescence: BST2 Antibody (120G8.04) - Bulk Size [DDX0390-HD10] - Staining of murine peyer's patch: BST-2

Immunohistochemistry: BST2 Antibody (120G8.04) - Bulk Size [DDX0390-HD10] - IHC staining of murine spleen cryosections

Flow Cytometry: BST2 Antibody (120G8.04) - Bulk Size [DDX0390-HD10] - Facs sorting of mouse PDCs (120G8/CD11c)

Flow Cytometry: BST2 Antibody (120G8.04) - Bulk Size [DDX0390-HD10] - BST2 Antibody (120G8.04) [DDX0390-HD10] - In vivo depletion of mouse PDCs (gated on CD11c+CD3- cells)

Product Discontinued

BST2 Antibody (120G8.04) - Bulk Size Summary

• Immunogen: mouse plasmatocytoid DCs (pDCs)
• Specificity: Mouse pDCs/BST-2/IFN producing cells (IPC) (extracellular domain)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Rat
• Gene: BST2
• Purity: Ion exchange chromatography

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry Free-Floating
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • In vivo assay 50-200 ug
• Application Notes: Monoclonal antibody 120G8.04 may be used between at 1-10 ug/ml. For pDCs in vivo depletion in Balb /c mice, mAb 120G8 was used between 50-200 ug / injection. Use in Immunohistochemistry free floating reported in scientific literature (PMID: 31207335).

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 31339007).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris-NaCl (pH 8.0)
• Preservative: No Preservative
• Concentration: 2 mg/ml
• Purity: Ion exchange chromatography

Notes

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

Alternate Names for BST2 Antibody (120G8.04) - Bulk Size

• bone marrow stromal antigen 2
• bone marrow stromal cell antigen 2
• BST2
• BST-2
• CD317 antigen
• CD317
• HM1.24 Antigen
• NPC-A-7
• PDCA-1
• Tetherin

Background

Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for BST2 Antibody (DDX0390-HD10)(2)

Publications using DDX0390-HD10

• Pan ZJ, Horton CG, Lawrence C, Farris AD. Plasmacytoid dendritic cells and type 1 IFN promote peripheral expansion of Foxp3(+) regulatory T cells specific for the ubiquitous RNA-binding nuclear antigen La/SS-B. Clin Exp Immunol 2016-05-26 [PMID: 27227559] (In Vivo, Mouse)
• Jiao J, Dragomir AC, Kocabayoglu P et al. Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils. J Immunol 2014-04-01 [PMID: 24591364] (In Vivo, Mouse)

Bioinformatics

• Gene Symbol: BST2