Breast carcinoma amplified sequence 3 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 0.2 mg/ml

Breast carcinoma amplified sequence 3 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 18 amino acids near the amino terminus of human BCAS3 .

  Source: Synthetic

  (Accession #: EAW51415)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: BCAS3
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-77125.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for Breast carcinoma amplified sequence 3 Antibody Blocking Peptide

• BCAS4/BCAS3 fusion
• breast carcinoma amplified sequence 3
• breast carcinoma amplified sequence 4/3 fusion protein
• breast carcinoma-amplified sequence 3
• DKFZp686O1527
• FLJ20128
• GAOB1
• MAAB
• metastasis associated antigen of breast cancer
• MGC4973
• protein Maab1

Background

BCAS3 acts as an ERalpha coactivator in breast cancer cells. It has been demonstrated that PELP1, a newly described ERalpha coregulator, is recruited to BCAS3 chromatin and activates its expression. Analysis of the BCAS3 sequence for functional motifs and evidence from biochemical fractionation suggested that BCAS3 acts as a transcriptional coactivator. Results from chromatin immunoprecipitation, reporter assays, and expression studies further validated the coactivator function of BCAS3 for ERalpha. BCAS3 physically associated with histone H3 and histone acetyltransferase complex protein P/CAF and possessed histone acetyltransferase activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: BCAS3