beta Adducin Antibody


Western Blot: beta Adducin Antibody [H00000119-D01P] - Analysis of ADD2 expression in transfected 293T cell line by ADD2 polyclonal antibody.Lane 1: ADD2 transfected lysate(80.80 KDa).Lane 2: Non-transfected lysate.

Product Details

Reactivity HuSpecies Glossary
Applications WB, ELISA
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Order Details

beta Adducin Antibody Summary

ADD2 (AAH65525.1, 1 a.a. ~ 726 a.a) full-length human protein.
Protein G purified
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Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
Protein G purified


  • Western Blot
Application Notes
This antibody is useful for Western Blot

Reactivity Notes

This product is reactive against Human.


This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for beta Adducin Antibody

  • ADDBErythrocyte adducin subunit beta
  • adducin 2 (beta)
  • beta adducin
  • beta-adducin


Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Various adducin beta mRNAs, alternatively spliced at 3'end and/or internally spliced and encoding different isoforms, have been described. The functions of all the different isoforms are not known.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


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Contact Information

Product PDFs


Gene Symbol ADD2

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