Recombinant Human BCAS2 Protein

Images

 
SDS-Page: Recombinant Human BCAS2 Protein [NBP1-50992] - 15 % SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.25 mg/ml

Order Details

Recombinant Human BCAS2 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-225 of Human BCAS2

Source: E.coli

Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMAGT GLVAGEVVVD ALPYFDQGYE APGVREAAAA LVEEETRRYR PTKNYLSYLT APDYSAFETD IMRNEFERLA ARQPIELLSM KRYELPAPSS GQKNDITAWQ ECVNNSMAQL EHQAVRIENL ELMSQHGCNA WKVYNENLVH MIEHAQKELQ KLRKHIQDLN WQRKNMQLTA GSKLREMESN WVSLVSKNYE IERTIVQLEN EIYQIKQQHG EANKENIRQD F

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
BCAS2
Purity
>85%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
30.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 5mM DTT, 0.2M NaCl
Preservative
No Preservative
Concentration
0.25 mg/ml
Purity
>85%, by SDS-PAGE

Alternate Names for Recombinant Human BCAS2 Protein

  • breast carcinoma amplified sequence 2
  • Breast carcinoma-amplified sequence 2
  • DAM1DNA amplified in mammary carcinoma 1 protein
  • pre-mRNA-splicing factor SPF27
  • Snt309
  • SPF27
  • spliceosome associated protein, amplified in breast cancer
  • Spliceosome-associated protein SPF 27

Background

BCAS2, also known as pre-mRNA-splicing factor SPF27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. It is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligand-independent manner) with TRbeta (thyroid hormone receptor beta), ERalpha (estrogen receptor alpha), ERbeta, PR (progesterone receptor) and PPARgamma (peroxisome proliferator-activated receptor gamma). This protein functions as an ER co-activator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer. Recombinant human BCAS2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB100-338
Species: Hu, Mu, Rt, Po, Ha, Mk
Applications: WB, Flow, ICC/IF, IHC, IP
NB100-294
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP, MiAr
NBP1-31354
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-83936
Species: Hu
Applications: WB, IHC, IHC-P
NB100-56077
Species: Hu
Applications: WB, IHC, IHC-P, IP
NB600-669
Species: Hu, Mu
Applications: WB, ICC/IF
NB100-294
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP, MiAr
NB100-558
Species: Hu
Applications: WB, ChIP, IHC, IHC-P, IP
NBP2-12892
Species: Hu
Applications: WB, ICC/IF
NBP1-06556
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IP
AF6028
Species: Hu
Applications: WB, IHC
NBP1-85720
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-31348
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
H00000699-D01P
Species: Hu, Mu
Applications: WB, ICC/IF, PLA
NLS1071
Species: Hu
Applications: IHC-P
NBP1-32775
Species: Hu, Mu, Rt
Applications: WB, ChIP, ICC/IF, IHC, IHC-P, IP
NBP1-91786
Species: Hu
Applications: IHC, IHC-P
NBP1-89979
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NB100-56633
Species: Hu
Applications: WB
NBP1-50992
Species: Hu
Applications: PAGE

Publications for BCAS2 Protein (NBP1-50992) (0)

There are no publications for BCAS2 Protein (NBP1-50992).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for BCAS2 Protein (NBP1-50992) (0)

There are no reviews for BCAS2 Protein (NBP1-50992). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for BCAS2 Protein (NBP1-50992) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional BCAS2 Products

Bioinformatics Tool for BCAS2 Protein (NBP1-50992)

Discover related pathways, diseases and genes to BCAS2 Protein (NBP1-50992). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for BCAS2 Protein (NBP1-50992)

Discover more about diseases related to BCAS2 Protein (NBP1-50992).
 

Pathways for BCAS2 Protein (NBP1-50992)

View related products by pathway.

PTMs for BCAS2 Protein (NBP1-50992)

Learn more about PTMs related to BCAS2 Protein (NBP1-50992).
 

Research Areas for BCAS2 Protein (NBP1-50992)

Find related products by research area.

Blogs on BCAS2

There are no specific blogs for BCAS2, but you can read our latest blog posts.

Customers Who Bought This Also Bought

BCAS2 Antibody
NB110-40681

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Recombinant Human BCAS2 Protein and receive a gift card or discount.

Bioinformatics

Gene Symbol BCAS2