BCAP/PIK3AP1 Antibody [Alexa Fluor® 405]

• Reactivity: Hu, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 405

BCAP/PIK3AP1 Antibody [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human BCAP
  Met462-Leu650
  Accession # Q6ZUJ8
• Specificity: Detects endogenous human and mouse BCAP in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BCAP/PIK3AP1 Antibody [Alexa Fluor® 405]

• 1810044J04Rik
• B cell adaptor protein
• BCAP
• BCAPB-cell adapter for phosphoinositide 3-kinase
• B-cell phosphoinositide 3-kinase adapter protein 1
• FLJ35564
• phosphoinositide 3-kinase adapter protein 1
• phosphoinositide-3-kinase adaptor protein 1
• Pik3ap1
• RP11-34E5.3

Background

BCAP (B-cell adaptor for phosphoinositide 3-kinase (PI3K)) participates in linking the B cell antigen receptor (BCR) with the PI3K pathway. Tyrosine phosphorylation of BCAP by BCR-associated protein tyrosine kinases, such as Syk and Btk, generates binding sites for the p85 subunit of PI3K, resulting in activation of the PI3K pathway. Human and mouse BCAP contain 3 YXXM SH2 binding motifs for interaction with PI3K.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.