ATP6V0A2 Antibody

Product Discontinued

ATP6V0A2 Antibody Summary

• Immunogen: ATP6V0A2 (NP_036595, 198 a.a. ~ 305 a.a) partial recombinant protein with GST tag.GYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHKVKKICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRVIQVKK
• Specificity: ATP6V0A2 - ATPase, H+ transporting, lysosomal V0 subunit a isoform 2
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: ATP6V0A2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50% Glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ATP6V0A2 Antibody

• A2
• ARCL
• ATP6A2
• ATP6N1D
• ATP6V0
• ATPase, H+ transporting, lysosomal V0 subunit a isoform 2
• ATPase, H+ transporting, lysosomal V0 subunit a2
• infantile malignant osteopetrosis
• J6B7
• Lysosomal H(+)-transporting ATPase V0 subunit a2
• regeneration and tolerance factor
• RTF
• STV1
• TJ6A2V-ATPase
• TJ6M
• TJ6S
• Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2
• vacuolar proton translocating ATPase 116 kDa subunit a
• V-ATPase 116 kDa isoform a2
• v-ATPase 116 kDa
• VPH1
• V-type proton ATPase 116 kDa subunit a isoform 2
• v-type proton ATPase 116 kDa subunit a
• WSS

Background

The multisubunit vacuolar-type proton pump (H(+)-ATPase or V-ATPase) is essential for acidification of diverse cellular components, including endosomes, lysosomes, clathrin-coated vesicles, secretory vesicles, and chromaffin granules, and it is found at high density in the plasma membrane of certain specialized cells. H(+)-ATPases are comprised of a peripheral V(1) domain and an integral membrane V(0) domain; ATP6V0A2 is a component of the V(0) domain (Smith et al., 2003 [PubMed 14580332]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ATP6V0A2 Antibody (H00023545-A01)(1)

Publication using H00023545-A01

• Lu X, Garrelds IM, Wagner CA et al. (Pro)renin receptor is required for prorenin-dependent and -independent regulation of vacuolar H+-ATPase activity in MDCK.C11 collecting duct cells. Am J Physiol Renal Physiol 2013-03-22 [PMID: 23698123]

Bioinformatics

• Gene Symbol: ATP6V0A2
• Entrez:
  • 23545(Human)
• Uniprot:
  • NP_036595(Human)