Recombinant Human Artemis Protein

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SDS-Page: Recombinant Human Artemis Protein [H00064421-Q01] - 12.5% SDS-PAGE Stained with Coomassie Blue.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, PA, PAGE, AP

Order Details

Recombinant Human Artemis Protein Summary

Description
A recombinant protein with a N-terminal GST tag corresponding to the amino acid sequence 481-577 of Human Artemis

Source: Wheat Germ

Amino Acid Sequence: ICPKDTYSDLKSRDKDVTIVPSTGEPTTLSSETHIPEEKSLLNLSTNADSQSSSDFEVPSTPEAELPKREHLQYLYEKLATGESIAVKKRKCSLLDT

Details of Functionality
This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.
Source
Wheat germ
Protein/Peptide Type
Partial Recombinant Protein
Gene
DCLRE1C
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Theoretical MW
36.41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Purity
>80% by SDS-PAGE and Coomassie blue staining

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human Artemis Protein

  • ASCID
  • DCLREC1C
  • DNA cross-link repair 1C protein
  • DNA cross-link repair 1C
  • EC 3.1
  • FLJ36438
  • hSNM1C
  • protein artemis
  • Protein A-SCID
  • PSO2 homolog
  • RS-SCID
  • severe combined immunodeficiency, type a (Athabascan)
  • SNM1 homolog C
  • SNM1CS. cerevisiae)
  • SNM1-like protein

Background

This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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H00064421-Q01
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Applications: WB, ELISA, PA, PAGE, AP

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Bioinformatics

Gene Symbol DCLRE1C