ARFGEF2 Antibody

ELISA: ARFGEF2 Antibody [35480002]

Product Discontinued

ARFGEF2 Antibody Summary

• Immunogen: This antibody is specific for the N Terminus Region of the target protein.
• Specificity: This product is specific for Human ARFGEF2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ARFGEF2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
• Application Notes: This product is useful in Immunohistochemistry-Paraffin and has been QC tested in ELISA against recombinant protein only.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for ARFGEF2 Antibody

• ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldinA-inhibited)
• ARFGEP2
• BIG2brefeldin A-inhibited guanine nucleotide-exchange protein 2
• Brefeldin A-inhibited GEP 2
• dJ1164I10.1
• FLJ23723
• PVNH2

Background

BIG2 promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. ARFGEF2 plays an important role in vesicular and membrane trafficking from the trans-golgi network. It is also involved in the activation of ARFs (1,5, and 6) by accelerating replacement of bound GDP with GTP. It also acts as the activator of ADP-ribosylation factor GTPases that are essential for regulating vesicular traffic among intracellular organelles.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ARFGEF2 Antibody (35480002)(2)

Publications using 35480002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Review for ARFGEF2 Antibody (35480002) (1)

Average Rating: 3

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer MiAr Human 12/18/2018

Summary

• Application: Microarray
• Sample Tested: EDTA Plasma
• Species: Human
• Lot: T01226A01

Bioinformatics

• Gene Symbol: ARFGEF2
• Entrez:
  • 10564(Human)
• Uniprot:
  • Q9Y6D5(Human)