This protein is not active and should not be used for experiments requiring activity.
>80% by SDS-PAGE and Coomassie blue staining
Use in Functional Assay reported in scientific literature (PMID: 24282027). Product may contain endotoxins and is not suitable for use with live cells.
71.1 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Human ARFGAP1 Protein
ADP-ribosylation factor 1 GTPase activating protein
ADP-ribosylation factor 1 GTPase-activating protein
ADP-ribosylation factor GTPase activating protein 1
ADP-ribosylation factor GTPase-activating protein 1
ARF GAP 1
ARF1-directed GTPase-activating protein
The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
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