AMTN Antibody

Immunohistochemistry-Paraffin: AMTN Antibody [NBP1-80809] - Staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.

• Reactivity: Hu
• Applications: IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

AMTN Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: SLPQLKPALGLPPTKLAPDQGTLPNQQQSNQVFPSLSLIPLTQMLTLGPDLHLLNPAAGMTPGTQTHPLTLGGLNVQQQLHPHVLPIFVTQLGAQ
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: AMTN
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  AMTN Protein (NBP1-80809PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for AMTN Antibody

• amelotin
• MGC148132
• MGC148133
• RSTI689
• UNQ689

Background

The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for AMTN Antibody (NBP1-80809)(2)

Publications using NBP1-80809

• Mark RB and Marc GA Utility of Alternative Promoters for Foreign Gene Expression Using the Baculovirus Expression Vector System Viruses 2022-11-29 [PMID: 36560674]
  
  Details:
  The supernatants of infections with SEAP-producing rBEVs were harvested by centrifugation at 1000× g for 10 min.
• Lindqvist R, Benz C, Sereikaite V et al. A Syntenin Inhibitor Blocks Endosomal Entry of SARS-CoV-2 and a Panel of RNA Viruses Viruses 2022-10-06 [PMID: 36298757] (ICC/IF, Human)
  
  Details:
  Dilution used in ICC 1:500

Bioinformatics

• Gene Symbol: AMTN
• Entrez:
  • 401138(Human)
• Uniprot:
  • Q6UX39(Human)