AMTN Products

Description

The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM]

Bioinformatics

Entrez	401138 Human
Uniprot	NP_997722 Human NP_997722.1 Human Q6UX39 Human
Product By Gene ID	401138
Alternate Names	MGC148133 MGC148132 UNQ689 RSTI689 amelotin

Diseases related to AMTN

Discover more about diseases related to AMTN.

Exanthema
Neoplasms
Amelogenesis Imperfecta
Nervousness
Odontogenic Tumors
Odontoma
Basal Cell Carcinoma
Fibroma
Calcifying Odontogenic Cyst
Carcinoma
Loss Of Chromosome 4
Dental Fluorosis, Acquired
Exotropia
Tooth Abnormalities
Dwarfism
Hereditary Diseases
Ameloblastoma
Tooth, Supernumerary
Delayed Puberty

Pathways for AMTN

View related products by pathway and learn more about each of the pathways below.

Amelogenesis
Secretion
Regeneration
Enamel Mineralization
Cell Proliferation
Localization
Tooth Eruption
Cell Adhesion
Protein Secretion
Ameloblast Differentiation
Notch Signaling Pathway
Tissue Development
System Development
Tissue Regeneration
Cellular Localization
Nervous System Development
Pathogenesis
Protein Stabilization
Corticosterone Secretion

PTMs for AMTN

Learn more about PTMs related to AMTN.

Phosphorylation
Glycosylation

Bioinformatics Tool for AMTN

Discover related pathways, diseases and genes to AMTN. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.