AlphaB Crystallin/CRYAB Antibody [DyLight 488]


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Product Details

Reactivity Hu, Mu, Rt, Po, Bv, Ha, Pm, Rb, ShSpecies Glossary
Applications WB, ICC/IF
DyLight 488

AlphaB Crystallin/CRYAB Antibody [DyLight 488] Summary

A synthetic peptide made to a C-terminal region of the human Crystallin AB protein (within residues 100-175). [Swiss-Prot P02511]
Predicted Species
Mouse (92%), Rat (100%), Porcine (100%), Sheep (100%), Rabbit (100%), Hamster (100%), Primate (100%), Bovine (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
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  • Western Blot
  • Immunocytochemistry/Immunofluorescence
Application Notes
This Crystallin AB antibody is useful for Western blot analysis, where a band is seen at ~20 kDa. There is also a band of greater intensity at ~40 kDa that may be an aggregated heteromeric complex. **CryAB aggregates with homologous proteins, including CryAA and the small heat shock protein HSP28, to form large heteromeric complexes.

Reactivity Notes

Predicted to react with rat, sheep, rabbit, monkey, hamster, cow, and pig based on 100% sequence homology. Immunogen sequence has 92% homology to mouse.

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Immunogen affinity purified


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for AlphaB Crystallin/CRYAB Antibody [DyLight 488]

  • alpha B crystallin
  • alpha(B)-crystallin
  • AlphaB Crystallin
  • alpha-crystallin B chain
  • CRYA2
  • CRYA2alpha crystallin B chain
  • crystallin, alpha B
  • CTPP2
  • Heat shock protein beta-5
  • heat-shock 20 kD like-protein
  • HSPB5
  • Renal carcinoma antigen NY-REN-27
  • Rosenthal fiber component


Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage. It may also play an important role in the Golgi reorganization during cell division. CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Biotin Labeled NB100-2520B
DyLight 550 Labeled NB100-2520R
DyLight 650 Labeled NB100-2520C
HRP Labeled NB100-2520H

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Gene Symbol CRYAB