Alpha Fodrin Antibody (SPTAN1/3352) [Allophycocyanin]

• Reactivity: Hu
• Applications: IHC, MA
• Clone: SPTAN1/3352
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

Alpha Fodrin Antibody (SPTAN1/3352) [Allophycocyanin] Summary

• Immunogen: Recombinant fragment of human Alpha Fodrin protein (around aa 2351-2475) (exact sequence is proprietary)) (Uniprot: Q13813)
• Localization: Cytoplasm
• Isotype: IgG2c Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SPTAN1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
  • Protein Array
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Others not known.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for Alpha Fodrin Antibody (SPTAN1/3352) [Allophycocyanin]

• Alpha-II spectrin
• EIEE5
• FLJ17738
• FLJ44613
• Fodrin alpha chain
• NEAS
• spectrin alpha chain, brain
• spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
• Spectrin, non-erythroid alpha chain
• SPTA2

Background

SPTAN1/Alpha II-spectrin is one of two polypeptide chains (alpha and beta) that are part of the fodrin tetramer. Fodrin functions to link actin filaments to the plasma membrane and is a major neuronal cytoskeletal protein. Fodrin has been linked to neurogenerative and autoimmune diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPTAN1