Alpha Fodrin Antibody (JU32-09)

Western Blot: Alpha Fodrin Antibody (JU32-09) [NBP2-75405] - Analysis of Alpha Fodrin on different lysates using anti-Alpha Fodrin antibody at 1/500 dilution.Positive control:Lane 1: Hela Lane 2: Jurkat Lane 3: NIH-3T3Lane 4:Rat brain Lane 5:Mouse brain

Immunohistochemistry-Paraffin: Alpha Fodrin Antibody (JU32-09) [NBP2-75405] - Analysis of paraffin-embedded mouse cerebellum tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin.

Immunohistochemistry-Paraffin: Alpha Fodrin Antibody (JU32-09) [NBP2-75405] - Analysis of paraffin-embedded human liver cancer tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin.

Immunohistochemistry-Paraffin: Alpha Fodrin Antibody (JU32-09) [NBP2-75405] - Analysis of paraffin-embedded human pancreas tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin.

Product Discontinued

Alpha Fodrin Antibody (JU32-09) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Synthetic peptide within Human Alpha Fodrin aa 46-95 / 2,472. (SwissProt: Q13813 Human; SwissProt: P16546 Mouse; SwissProt: P16086 Rat)
• Localization: Cytoskeleton.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: SPTAN1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 285 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Alpha Fodrin Antibody (JU32-09)

• Alpha-II spectrin
• EIEE5
• FLJ17738
• FLJ44613
• Fodrin alpha chain
• NEAS
• spectrin alpha chain, brain
• spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
• Spectrin, non-erythroid alpha chain
• SPTA2

Background

SPTAN1/Alpha II-spectrin is one of two polypeptide chains (alpha and beta) that are part of the fodrin tetramer. Fodrin functions to link actin filaments to the plasma membrane and is a major neuronal cytoskeletal protein. Fodrin has been linked to neurogenerative and autoimmune diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPTAN1