alpha-2C Adrenergic R/ADRA2C Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

alpha-2C Adrenergic R/ADRA2C Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human ADRA2C.
  
  

  Source: E. coli

  Amino Acid Sequence: LTASRSPGPGGRLSRASSRSVEFFLSR

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: ADRA2C
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-33845.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 20 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for alpha-2C Adrenergic R/ADRA2C Recombinant Protein Antigen

• a-2C AdrenergicR
• ADRA2C
• ADRA2L2
• ADRA2L2alpha-2CAR
• ADRA2RL2
• ADRARL2
• adrenergic, alpha-2C-, receptor
• Alpha-2 adrenergic receptor subtype C4
• alpha2-AR-C4
• alpha-2C Adrenergic R
• alpha-2C adrenergic receptor
• alpha2C AdrenergicR
• Alpha-2C adrenoceptor
• Alpha-2C adrenoreceptor
• alpha-2C-adrenergic receptor
• ALPHA2CAR
• Alpha-2CAR

Background

The alpha-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. There are 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha2C is required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: ADRA2C