alpha-1B Adrenergic R/ADRA1B Antibody

Immunohistochemistry-Paraffin: alpha-1B Adrenergic R/ADRA1B Antibody [NBP1-02348] - Staining of human smooth muscle cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Product Discontinued

alpha-1B Adrenergic R/ADRA1B Antibody Summary

• Immunogen: Synthetic 20 amino acid peptide from C-terminal cytoplasmic domain of human ADRA1B.
• Specificity: Human ADRA1B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (95%), Primate (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADRA1B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (95%), Mouse (85%), Hamster (85%), Elephant (85%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for alpha-1B Adrenergic R/ADRA1B Antibody

• a-1B AdrenergicR
• ADRA1
• ADRA1B
• adrenergic, alpha-1B-, receptor
• alpha-1B Adrenergic R
• alpha-1B adrenergic receptor
• alpha1B AdrenergicR
• Alpha-1B adrenoceptor
• Alpha-1B adrenoreceptor
• alpha-1B-adrenergic receptor
• ALPHA1BAR

Background

The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADRA1B
• Entrez:
  • 147(Human)
• Uniprot:
  • P35368()