AKAP6 Antibody

Western Blot: AKAP6 Antibody [NB300-869] - Detection by western blot of AKAP6 in mouse tissue using NB300-869 at 0.5 ug/ml.

• Reactivity: Mu, Hu, Rt, Po, Bv, Ca
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

AKAP6 Antibody Summary

• Description: Novus Biologicals Goat AKAP6 Antibody (NB300-869) is a polyclonal antibody validated for use in WB and ELISA. Anti-AKAP6 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence LTMSVTLSPLRSQ-C corresponding to N-Terminus according to NP_004265.3.
• Predicted Species: Human (100%), Rat (100%), Porcine (100%), Bovine (100%), Canine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: AKAP6
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:16000
  • Western Blot 1:100 - 1:2000
• Application Notes: WB: A 190 kDa band of mouse heart and of mouse parotid (PMID: 20164376).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for AKAP6 Antibody

• A kinase (PRKA) anchor protein 6
• ADAP6A-kinase anchor protein 6
• AKAP100A-kinase anchor protein 100 kDa
• AKAP-6
• KIAA0311AKAP 100
• mAKAPMGC165020
• PRKA6ADAP100
• protein kinase A anchoring protein 6
• Protein kinase A-anchoring protein 6

Background

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function ofbinding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations withinthe cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brainregions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclearmembrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for AKAP6 Antibody (NB300-869)(2)

Publications using NB300-869

• Wu CY, DiJulio DH, Jacobson KL et al. The contribution of AKAP5 in amylase secretion from mouse parotid acini. Am J Physiol Cell Physiol. 2010-05-01 [PMID: 20164376] (WB, Mouse)
  
  Details:
  WB: The AkAP6 antibody identified full length and degradation products in mouse parotid acini and mouse heart cells, Fig 1C.
• McCartney S, Little BM, Langeberg LK, Scott JD. Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum. J Biol Chem 1995-04-21 [PMID: 7721854]

Bioinformatics

• Gene Symbol: AKAP6
• Entrez:
  • 9472(Human)
  • 238161(Mouse)
  • 64553(Rat)
• Uniprot:
  • Q13023(Human)