AFAP Antibody (16F50) [PE]

Product Discontinued

AFAP Antibody (16F50) [PE] Summary

• Description: This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
• Immunogen: Human recombinant AFAP
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: AFAP1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • ELISA
  • Flow Cytometry

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for AFAP Antibody (16F50) [PE]

• actin filament associated protein 1
• AFAP
• AFAP1
• AFAP-110
• FLJ56849

Background

AFAP, or Actin filament-associated protein 1, contains a 81 kDa and a 90 kDa isoform, and is involved in the manipulation of actin filaments to form network or bundle structures and the regulation of cell-matrix linkage. Disease research is currently being conducted with AFAP and its relation to familial adenomatous polyposis, adenocarcinoma, breast cancer, prostate adenocarcinoma, prostatitis, polyposis, prostate cancer, and carcinoma. This protein interacts with PRKCB, PRKCD, PRKCG, ACTC1, and PRKCZ during the processes of signal transduction regulation and mechanical stimulus response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for AFAP Antibody (NBP2-22004PE)(1)

Publication using NBP2-22004PE

• Chan JS, Tan MJ, Sng MK et al. Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress Cell Death Dis Jan 19 2017 [PMID: 28102840] (FLOW, Human). Cell Death Dis. 2017-01-19 [PMID: 28102840] (FLOW, Human)
  
  Details:
  This citation used the PE version of this antibody.

Bioinformatics

• Gene Symbol: AFAP1