ADAMTS8 Antibody (5A3) - Azide and BSA Free

Sandwich ELISA: ADAMTS8 Antibody (5A3) [H00011095-M01] - Detection limit for recombinant GST tagged ADAMTS8 is approximately 0.3ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, MA
• Clone: 5A3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

ADAMTS8 Antibody (5A3) - Azide and BSA Free Summary

• Immunogen: ADAMTS8 (NP_008968, 781 a.a. ~ 890 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. RPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLCPL
• Specificity: ADAMTS8 (5A3)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ADAMTS8
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Protein Array
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ADAMTS8 Antibody (5A3) - Azide and BSA Free

• a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 8
• ADAM metallopeptidase with thrombospondin type 1 motif, 8
• ADAMTS8
• ADAMTS-8
• ADAM-TS8A disintegrin and metalloproteinase with thrombospondin motifs 8
• EC 3.4.24
• EC 3.4.24.-
• EC 3.4.24.14
• EC 3.4.24.82
• FLJ41712
• METH-2
• METH2ADAM-TS 8
• METH-8

Background

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ADAMTS8 Antibody (H00011095-M01)(1)

Publication using H00011095-M01

• Klee, George G, Vasmatzis, George, Kosari et al. EXTRACELLULAR AND MEMBRANE-ASSOCIATED PROSTATE CANCER MARKERS FreshPatents 2010-02-04 (ELISA, Human)

Bioinformatics

• Gene Symbol: ADAMTS8
• Entrez:
  • 11095(Human)
• OMIM:
  • 605175(Human)
• Uniprot:
  • NP_008968(Human)