SMN Products

Antibodies
SMN Antibody (5H1)
SMN Antibody (5H1)
NBP2-37594
Species: Hu, Pm
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
SMN Antibody (2F1)
SMN Antibody (2F1)
NBP2-37595
Species: Hu, Pm
Applications: WB, ELISA, Flow, IHC
Host: Mouse Monoclonal
Lysates
SMN Overexpression Lysate (Na ...
SMN Overexpression Lysate (Native)
NBL1-16243
Applications: WB
SMN Overexpression Lysate (Na ...
SMN Overexpression Lysate (Native)
NBP2-06396
Applications: WB

Description

SMN (Gemin 1) is the central component of a large oligomeric complex (SMN complex), including Gemins 2-7, that is necessary and sufficient for the in vivo assembly of Sm proteins onto the small nuclear (sn)RNAs that mediate pre-mRNA splicing. The SMN complex is found in the cytoplasm and nucleus. Within the nucleus, this protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). Spinal muscular atrophy, a motor neuron disorder, results from reduced levels or a mutation in the Gemin 1 protein.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Mouse
Rat
Product By Gene ID 6606
Alternate Names
  • SMNC
  • Gemin-1
  • Kugelberg-Welander disease)
  • survival of motor neuron 1, telomeric

Research Areas for SMN

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Neurodegeneration
Neuroscience
Transcription Factors and Regulators

PTMs for SMN

Learn more about PTMs related to SMN.

Cleavage
Methylation
Ubiquitination
Phosphorylation
Acetylation
Sumoylation

Bioinformatics Tool for SMN

Discover related pathways, diseases and genes to SMN. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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