ACE-2 Products

Antibodies
ACE-2 Antibody [Unconjugated] ...
ACE-2 Antibody [Unconjugated]
AF933
Species: Hu
Applications: WB, Simple Western, IHC, IP
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
ACE-2 Antibody [Unconjugated] ...
ACE-2 Antibody [Unconjugated]
AF3437
Species: Mu
Applications: WB, Simple Western, IHC, IP
Host: Goat Polyclonal
Formulation Catalog # Availability Price  
ACE-2 Antibody (171606) [Unco ...
ACE-2 Antibody (171606) [Unconjuga...
MAB933
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human ACE-2 ELISA Kit (Chemil ...
Human ACE-2 ELISA Kit (Chemilumine...
NBP2-66387
Species: Hu
Applications: ELISA
Proteins
Recombinant Human ACE-2 Prote ...
Recombinant Human ACE-2 Protein, CF
933-ZN
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Recombinant Mouse ACE-2 Prote ...
Recombinant Mouse ACE-2 Protein, CF
3437-ZN
Species: Mu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Recombinant Rat ACE-2 Protein ...
Recombinant Rat ACE-2 Protein, CF
4516-ZN
Species: Rt
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
RNAi
ACE-2 RNAi
ACE-2 RNAi
H00059272-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 59272
Alternate Names
  • EC 3.4.17
  • ACE-related carboxypeptidase
  • EC 3.4.17.23
  • Metalloprotease MPROT15
  • angiotensin-converting enzyme 2
  • Angiotensin-converting enzyme homolog
  • ACEHangiotensin I converting enzyme 2
  • DKFZp434A014
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

Research Areas for ACE-2

Find related products by research area and learn more about each of the different research areas below.

Immunology
Virology, Bacteria and Parasites

Bioinformatics Tool for ACE-2

Discover related pathways, diseases and genes to ACE-2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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