ZIM2 Antibody

Product Discontinued

ZIM2 Antibody Summary

• Immunogen: In vivo generated recominant protein fragment
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ZIM2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:2000
  • Immunocytochemistry/ Immunofluorescence 1:200

Reactivity Notes

C. elegans

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product was created from the ModEncode Project, a part of the NHGRI, and is sold by SDIX and Novus Biologicals. These C. elegans antibodies were generated in the labs of Jason Lieb, Susan Strome, Julie Ahringer, Arshad Desai, and Abby Dernburg.

Alternate Names for ZIM2 Antibody

• zinc finger imprinted 2
• zinc finger, imprinted 2
• ZNF656Zinc finger protein 656

Background

In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5' exons and have a common promoter, and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow, where ZIM2 and PEG3 genes do not share exons in common, and the imprinting status of ZIM2 is also not conserved amongst mammals. Additional 5' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ZIM2 Antibody (49270002)(1)

Publication using 49270002

• Sato-Carlton A, Nakamura-Tabuchi C, Chartrand SK et al. Phosphorylation of the synaptonemal complex protein SYP-1 promotes meiotic chromosome segregation bioRxiv 2017-10-31 [PMID: 29222184] (ICC/IF, C. elegans)

Bioinformatics

• Gene Symbol: ZIM2
• Entrez:
  • 177948(C. elegans)
• Uniprot:
  • O18067(C. elegans)