ZC3H12B Antibody - BSA Free

Western Blot: ZC3H12B Antibody [NBP1-77141] - Mouse brain tissue lysate with ZC3H12B antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry: ZC3H12B Antibody - BSA Free [NBP1-77141] - Immunohistochemistry of ZC3H12B in human brain tissue with ZC3H12B antibody at 5 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

ZC3H12B Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ZC3H12B Antibody - BSA Free (NBP1-77141) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZC3H12B. The immunogen is located within the first 50 amino acids of ZC3H12B. Amino Acid Squence: DSTEQGNADSEEWMSSE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ZC3H12B
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1 ug/ml
• Control Peptide:

  ZC3H12B Peptide (NBP1-77141PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for ZC3H12B Antibody - BSA Free

• MCP-induced protein 2
• zinc finger CCCH domain-containing protein 12B
• zinc finger CCCH-type containing 12B

Background

ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ZC3H12B
• Uniprot:
  • NP_001010888(Human)