ZC3H12B Antibody

Images

 
Western Blot: ZC3H12B Antibody [NBP1-77141] - Mouse brain tissue lysate with ZC3H12B antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry-Paraffin: ZC3H12B Antibody [NBP1-77141] - Human brain tissue with ZC3H12B antibody at 5 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

ZC3H12B Antibody Summary

Immunogen
Antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZC3H12B. The immunogen is located within the first 50 amino acids of ZC3H12B.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ZC3H12B
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
ZC3H12B Peptide (NBP1-77141PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ZC3H12B Antibody

  • MCP-induced protein 2
  • zinc finger CCCH domain-containing protein 12B
  • zinc finger CCCH-type containing 12B

Background

ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ZC3H12B
Uniprot