Vanilloid R1/TRPV1 Antibody [FITC]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
FITC

Vanilloid R1/TRPV1 Antibody [FITC] Summary

Immunogen
A genomic peptide made to a C-terminal region of the human TRPV1 protein (within residues 725-839). [Swiss-Prot Q8NER1]
Localization
Cell junction: synapse. Multi-pass membrane protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPV1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This TRPV1 antibody is useful for ICC/IF and IHC-paraffin embedded tissues. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

Reactivity Notes

Human and mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Vanilloid R1/TRPV1 Antibody [FITC]

  • Capsaicin Receptor
  • Osm-9-like TRP channel 1
  • OTRPC1
  • transient receptor potential cation channel subfamily V member 1
  • transient receptor potential cation channel, subfamily V, member 1
  • transient receptor potential vanilloid 1a
  • transient receptor potential vanilloid 1b
  • TRPV1
  • Vanilloid R1
  • Vanilloid receptor 1
  • vanilloid receptor subtype 1
  • VanilloidR1
  • VR1
  • VR1DKFZp434K0220

Background

TRPV1, a ligand-gated cation channel expressed in peripheral nociceptors, induces pain when activated by capsaicin. TRPV1 affects the inhibitory control of neurons by integrating multiple noxious signals, which is critical in chronic pain. Blocking TRPV1 is becoming a more common approach to suppression of pathological pain. When inflammation is present, TRPV1 causes an itch response. Dietary salt content can affect the concentration and activity of TRPV1, which in turn can affect kidney activities resulting in renin regulation. TRPV1 is also critically involved in thermal activation and detection of infrared radiation. Finally, TRPV1 is dysfunctional in hypertrophic hearts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Vanilloid R1/TRPV1 Products

Bioinformatics Tool for Vanilloid R1/TRPV1 Antibody (NBP1-71774F)

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Diseases for Vanilloid R1/TRPV1 Antibody (NBP1-71774F)

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Bioinformatics

Gene Symbol TRPV1
Entrez