Vanilloid R1/TRPV1 Antibody [Alexa Fluor® 405]

• Reactivity: Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 405

Vanilloid R1/TRPV1 Antibody [Alexa Fluor® 405] Summary

• Immunogen: KLH-coupled rat Vanilloid R1/TRPV1 synthetic peptide
  RASLDSEESESPPQENSC
  Accession # O35433
• Specificity: Detects rat Vanilloid R1/TRPV1 in immunohistochemistry.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Vanilloid R1/TRPV1 Antibody [Alexa Fluor® 405]

• Capsaicin Receptor
• Osm-9-like TRP channel 1
• OTRPC1
• transient receptor potential cation channel subfamily V member 1
• transient receptor potential cation channel, subfamily V, member 1
• transient receptor potential vanilloid 1a
• transient receptor potential vanilloid 1b
• TRPV1
• Vanilloid R1
• Vanilloid receptor 1
• vanilloid receptor subtype 1
• VanilloidR1
• VR1
• VR1DKFZp434K0220

Background

VR1, also known as TRPV1 (Transient Receptor Potential Vanilloid 1) and capsaicin receptor, is a 115 kDa integral membrane ion channel that has six transmembrane domains and contains intracellular N-and C-termini. It contributes to normal pain and temperature sensation and also has a “sensory-effector” function. By alternative splicing, at least three VR1 isoforms are known. The sequence of residues 4-21 of rat VR1 is 78% and 28% identical to that of mouse and human VR1, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.