UbcH2/UBE2H Antibody [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Applications: WB, ELISA, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 594

UbcH2/UBE2H Antibody [Alexa Fluor™ Plus 594] Summary

• Immunogen: Produced in rabbits immunized with purified, recombinant Human UbcH2/UBE2H (Accession#: P62256; Met1-Leu183)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: UBE2H
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for UbcH2/UBE2H Antibody [Alexa Fluor™ Plus 594]

• E2-14K
• E2-20K
• EC 6.3.2.19
• UBC8
• UBC8E2-20K
• UBCH
• UbcH2
• UBE2H
• Ubiquitin carrier protein H
• ubiquitin-conjugating enzyme E2 H
• Ubiquitin-conjugating enzyme E2-20K
• ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8)
• ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
• Ubiquitin-protein ligase H

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: UBE2H