Troponin I Type 3 (cardiac) Antibody (2C9) - BSA Free

Images

 
Western Blot: Troponin I Type 3 (cardiac) Antibody (2C9) [NBP2-35336] - Analysis of clone 2C9 in human heart at 0.5 and 1.0 ug/mL
Immunohistochemistry-Paraffin: Troponin I Type 3 (cardiac) Antibody (2C9) [NBP2-35336] - Formalin fixed tissue section of human breast with 5 ug/mL concentration of Troponin I Type 3 (cardiac) antibody (clone 2C9) ...read more
Immunohistochemistry-Paraffin: Troponin I Type 3 (cardiac) Antibody (2C9) [NBP2-35336] - Analysis of FFPE tissue section of human heart using Troponin I antibody (clone 2C9) at 5 ug/mL concentration. The antibody ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clone
2C9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Order Details

Troponin I Type 3 (cardiac) Antibody (2C9) - BSA Free Summary

Immunogen
Partial recominant human Troponin 1 (between amino acids 1-200) [UniProt P19429]
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TNNI3
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 5 ug/mL
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 0.5 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for Troponin I Type 3 (cardiac) Antibody (2C9) - BSA Free

  • Cardiac troponin I
  • CMD1FF
  • CMD2A
  • CMH7MGC116817
  • CTnI
  • familial hypertrophic cardiomyopathy 7
  • RCM1
  • TNNC1
  • TNNC1troponin I, cardiac
  • TNNI3,
  • troponin I type 3 (cardiac)
  • troponin I, cardiac muscle
  • Troponin I/TNNI3

Background

Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium. This antibody reacts with subunit I of the troponin complex in human myocardium, where it is the only troponin I isotype present. It does not cross-react with troponin I of skeletal muscle cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Blogs on Troponin I Type 3 (cardiac).

Troponin I Type 3 (TnI, cardiac)
Troponin I is part of a heteromeric thin filament regulatory complex that governs skeletal and cardiac muscle contraction. Troponin I is composed of three subunits: troponin I (TnI), troponin T (TnT), and troponin C (TnC), and each of these components...  Read full blog post.

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Bioinformatics

Gene Symbol TNNI3
Entrez
Uniprot