TRMT12 Antibody [PerCP]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
PerCP

Order Details

TRMT12 Antibody [PerCP] Summary

Immunogen
Antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TYW2. The immunogen is located within the first 50 amino acids of TYW2. Amino Acid Squence: TQRYREYLQRQKLFDTQHR
Specificity
TYW2 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW2 are known to exist; this antibody will detect both isoforms
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRMT12
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Alternate Names for TRMT12 Antibody [PerCP]

  • Alpha-amino-alpha-carboxypropyl transferase TYW2
  • EC 2.1.1
  • EC 2.1.1.32
  • EC 2.5.1.-
  • FLJ20772
  • homolog of yeast tRNA methyltransferase
  • TRM12
  • tRNA methyltranferase 12 homolog (S. cerevisiae)
  • tRNA methyltranferase 12 homolog
  • tRNA methyltransferase 12 homolog (S. cerevisiae)
  • tRNA-yW synthesizing protein 2
  • tRNA-yW-synthesizing protein 2
  • TYW2tRNA wybutosine-synthesizing protein 2 homolog

Background

Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Blogs on TRMT12

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Bioinformatics

Gene Symbol TRMT12