Recombinant Human TAFA2/FAM19A2 Protein

SDS-Page: Human TAFA2/FAM19A2 Protein [NBP2-35034]

• Reactivity: Hu
• Applications: PAGE, Bioactivity
• Format: Carrier-Free
• Concentration: LYOPH

Recombinant Human TAFA2/FAM19A2 Protein Summary

• Description: A single, non-glycosylated polypeptide chain containing 101 amino acids corresponding to TAFA2/FAM19A2 Source: E. coli

  Uniprot ID: Q8N3H0

  Amino Acid Sequence: ANHHKAHHVK TGTCEVVALH RCCNKNKIEE RSQTVKCSCF PGQVAGTTRA APSCVDASIV EQKWWCHMQP CLEGEECKVL PDRKGWSCSS GNKVKTTRVT H

• Details of Functionality: TAFA2/FAM19A2 protein is fully biologically active when compared to standard. The biological activity is determined by its ability to enhance neurite outgrowth of E16E18 rat embryonic cortical neurons. rHuTAFA2, immobilized at 624 ug/mL on a 96 well plate, is able to significantly enhance neurite outgrowth.
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: FAM19A2
• Purity: >95%, by SDS-PAGE and HPLC
• Endotoxin Note: Less than 1 EU/ug of TAFA2/FAM19A2 as determined by LAL method.

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 11.2 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered concentrated solution in 2 x PBS, pH 7.4.
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: >95%, by SDS-PAGE and HPLC
• Reconstitution Instructions: Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.

Alternate Names for Recombinant Human TAFA2/FAM19A2 Protein

• Chemokine-like protein TAFA-2
• DKFZp761E1217
• DKFZp781P0552
• FAM19A2
• family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
• MGC42403
• TAFA2
• TAFA-2

Background

FAM19A2 also named TAFA2 , is a chemokinelike protein which is belonged to the FAM19/TAFA family. The family is a newly discovered and distantly related to MIP1alpha. It contains 5 members and TAFA proteins are highly expressed in specific brain regions. Like other members of the TAFA family, with the exception of TAFA5, mature TAFA1 contains 10 regularly spaced cysteine residues. Human FAM19A2 (TAFA2) is 97 % a.a. identical to mouse TAFA2. The biological functions of TAFA family members remain to be determined, but they are postulated to act as brainspecific chemokines or neurokines that take parts in regulators of immune and nervous cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: FAM19A2
• Uniprot:
  • Q8N3H0()
  • Q8N3H0()
  • Q8N3H0()