SPANXA1 Antibody [DyLight 650]

Product Discontinued

SPANXA1 Antibody [DyLight 650] Summary

• Immunogen: SPANX family, member A2. (Uniprot# Q9NS26)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SPANXA1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SPANXA1 Antibody [DyLight 650]

• B1
• C
• cancer/testis antigen family 11, member 1
• CT11.1
• CT11.2
• CT11.3
• CT11.4
• CTp11
• dJ171K16.1
• member A1
• NAP-X
• nuclear-associated protein SPAN-Xa
• SPANX family member A
• SPANX
• SPAN-X
• SPANXA
• SPAN-Xa
• SPANX-A
• SPANXA1 sperm protein associated with the nucleus, X-linked, family member A1
• SPANXA2
• SPANX-A2
• SPANXB
• SPAN-Xb
• SPANX-B
• SPANXC
• SPANX-C
• SPANXD
• SPANX-D
• sperm protein associated with the nucleus on the X chromosome A
• sperm protein associated with the nucleus, X chromosome, family member A1
• sperm protein associated with the nucleus, X-linked, family member A1

Background

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPANXA1