ELISA usage was reported in the scientific literature (PMID: 7692739). WB: Detects an approx. 120 kDa protein representing the sodium / calcium exchanger from guinea pig cardiac extract. Also detects 70 kDa and 160 kDa proteins representing a proteolytic fragment and non-reduced exchanger respectively. T-tubular membrane.
Read Publications using NB120-2869 in the following applications:
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
0.05% Sodium Azide
Alternate Names for Sodium-Calcium Exchanger Antibody (C2C12)
Na(+)/Ca(2+)-exchange protein 3
Na+/Ca2+ exchanger 3
NCX3sodium/calcium exchanger SLC8A3
sodium/calcium exchanger 3
solute carrier family 8 (sodium/calcium exchanger), member 3
solute carrier family 8 (sodium-calcium exchanger), member 3
The sodium/calcium exchanger of cardiac sarcolemma rapidly transports calcium during excitation-contraction coupling and is the dominant myocardial calcium efflux mechanism. The sodium/calcium exchanger uses the transmembrane sodium gradient to catalyze countertransport of calcium against its electrochemical gradient in a 3 sodium : 1 calcium exchange. Sodium/calcium exchange activity is present in excitable cells and in non-excitable cells.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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