SLC34A2 Antibody [ADC] - (Lifastuzumab Vedotin, Research Grade)

Human NaPi2b CHO-S Cells were stained with SLC34A2 and negative control protein respectively, washed and then followed by PE and analyzed with FACS

Immobilized Human SLC34A2, VLP at 5 ug/mL can bind SLC34A2 , EC50=0.06175 ug/mL.

Human NaPi2b HEK293 Cell Line were stained with SLC34A2and negative control protein respectively, washed and then followed by PE and analyzed with FACS, The EC50 is 0.9793 ug/mL.

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clonality: Monoclonal
• Host: Human
• Conjugate: ADC
• Concentration: LYOPH

SLC34A2 Antibody [ADC] - (Lifastuzumab Vedotin, Research Grade) Summary

• Description: This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).
  
  Lifastuzumab Vedotin is an ADC consisting of an anti-NaPi2b monoclonal antibody conjugated to the cytotoxic agent MMAE
  
  This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
• Immunogen: SLC34A2 (Uniprot: O95436)
• Source: CHO
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Purity: > 90% by SDS-PAGE and HPLC

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional
• Theoretical MW: 145 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: > 90% by SDS-PAGE and HPLC
• Reconstitution Instructions: Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for SLC34A2 Antibody [ADC] - (Lifastuzumab Vedotin, Research Grade)

• NAPI-3B
• NPTIIb
• sodium/phosphate cotransporter 2B
• solute carrier family 34 (sodium phosphate), member 2
• type II sodium-dependent phosphate transporter 3b

Background

SLC34A2 may be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. Mayhave a role in the synthesis of surfactant in lungs' alveoli

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.