SGK3 Antibody

Images

 
Immunohistochemistry-Paraffin: SGK3 Antibody [NLS7240] - Anti-SGK3 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more
Immunohistochemistry-Paraffin: SGK3 Antibody [NLS7240] - Analysis of anti-SGK3 antibody with human islet of langerhans at 1 ug/ml.
Immunohistochemistry-Paraffin: SGK3 Antibody [NLS7240] - Anti-SGK3 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bt, Ca, Ha, Bv, Ch, Eq, Mk, Pm, Rb, TrSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

SGK3 Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from internal region of human SGK3.
Localization
Cytoplasmic vesicle (By similarity). Early endosome (By similarity).
Specificity
Human SGK3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Rabbit (95%), Bovine (95%), Chicken (90%), Monkey (95%), Primate (95%), Turkey (90%), Equine (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SGK3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10-1:500
Publications
Read Publication using
NLS7240 in the following applications:

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Orangutan (100%), Gibbon (100%), Panda (100%), Marmoset (95%), Elephant (95%), Platypus (90%), Opossum (85%), Lizard (85%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SGK3 Antibody

  • CISK
  • DKFZp781N0293
  • EC 2.7.11
  • EC 2.7.11.1
  • serine/threonine-protein kinase Sgk3
  • serum/glucocorticoid regulated kinase 3
  • serum/glucocorticoid regulated kinase family, member 3
  • serum/glucocorticoid regulated kinase-like
  • Serum/glucocorticoid-regulated kinase 3
  • Serum/glucocorticoid-regulated kinase-like
  • SGK2
  • SGKLcytokine-independent survival kinase

Background

SGKL/SGK3, also known as CISK for cytokine-independent survival kinase, is a SGK type protein kinase. The protein contains a lipid-binding phox homology (PX) domain, which is required for targeting SGKL/SGK3 protein to the endosomal compartment. SGKL/SGK3 functions downstream of the phosphoinositide 3-kinase (PI3K) cascade and has been implicated in cell survival. The protein has been shown to be phosphorylated and activated by 3-phosphoinositide-dependent protein kinase 1 (PDK1), and to a lesser extent insulin-like growth factor-1, in vitro. Activated SGKL/SGK3 has been shown to phosphorylate glycogen synthase kinase 3 beta (GSK-3beta) in vitro. SGKL/SGK3 expression has been documented in many human tissues but was found to be most abundant in lung. ESTs have been isolated from human tissue libraries, including normal liver, breast and thyroid and cancerous spleen, ear and pancreas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: IHC-P

Publications for SGK3 Antibody (NLS7240)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-P.


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IHC-P
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Product General Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SGK3
Entrez
Uniprot