SGK3 Products

Antibodies
SGK3 Antibody
SGK3 Antibody
NBP1-80760
Species: Hu, Mouse
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
SGK3 Antibody
SGK3 Antibody
NBP2-20336
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
SGK3 Antibody
SGK3 Antibody
NLS7240
Species: Hu, Mu, Rt, Bt, Ca, Ha, Bovine, Chicken, Equine, Primate, Rabbit, Turkey, Monkey
Applications: IHC-P
Host: Rabbit Polyclonal
Lysates
SGK3 Overexpression Lysate (N ...
SGK3 Overexpression Lysate (Native)
NBP2-05212
Applications: WB
SGK3 Overexpression Lysate (N ...
SGK3 Overexpression Lysate (Native)
NBL1-15908
Applications: WB
SGK3 Overexpression Lysate (N ...
SGK3 Overexpression Lysate (Native)
NBL1-15909
Applications: WB
Proteins
SGK3 Recombinant Protein
SGK3 Recombinant Protein
H00023678-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, KA
SGK3 Partial Recombinant Prot ...
SGK3 Partial Recombinant Protein
H00023678-Q01
Species: Hu
Applications: WB, ELISA, PA
SGK3 Recombinant Protein Anti ...
SGK3 Recombinant Protein Antigen
NBP1-80760PEP
Species: Hu
Applications: AC
RNAi
SGK3 RNAi
SGK3 RNAi
H00023678-R04
Species: Hu
Applications: RNAi, RNAi SP
SGK3 RNAi
SGK3 RNAi
H00023678-R03
Species: Hu
Applications: RNAi, RNAi SP

Description

SGKL/SGK3, also known as CISK for cytokine-independent survival kinase, is a SGK type protein kinase. The protein contains a lipid-binding phox homology (PX) domain, which is required for targeting SGKL/SGK3 protein to the endosomal compartment. SGKL/SGK3 functions downstream of the phosphoinositide 3-kinase (PI3K) cascade and has been implicated in cell survival. The protein has been shown to be phosphorylated and activated by 3-phosphoinositide-dependent protein kinase 1 (PDK1), and to a lesser extent insulin-like growth factor-1, in vitro. Activated SGKL/SGK3 has been shown to phosphorylate glycogen synthase kinase 3 beta (GSK-3beta) in vitro. SGKL/SGK3 expression has been documented in many human tissues but was found to be most abundant in lung. ESTs have been isolated from human tissue libraries, including normal liver, breast and thyroid and cancerous spleen, ear and pancreas.

Bioinformatics

Entrez Human
Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 23678
Alternate Names
  • serum/glucocorticoid regulated kinase-like
  • EC 2.7.11
  • CISK
  • Serum/glucocorticoid-regulated kinase-like
  • EC 2.7.11.1
  • serum/glucocorticoid regulated kinase 3
  • SGK2
  • serine/threonine-protein kinase Sgk3
  • Serum/glucocorticoid-regulated kinase 3
  • SGKLcytokine-independent survival kinase
  • DKFZp781N0293
  • serum/glucocorticoid regulated kinase family, member 3

Research Areas for SGK3

Find related products by research area and learn more about each of the different research areas below.

GPCR
Protein Kinase

PTMs for SGK3

Learn more about PTMs related to SGK3.

Phosphorylation
Carboxylation
Reduction
Ubiquitination

Bioinformatics Tool for SGK3

Discover related pathways, diseases and genes to SGK3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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