SALM2/LRFN1 Antibody - BSA Free Summary
| Description |
Novus Biologicals Rabbit SALM2/LRFN1 Antibody - BSA Free (NBP1-77345) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee. |
| Immunogen |
Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LRFN1. The immunogen is located within amino acids 700 - 750 of LRFN1. Amino Acid Squence: HSYPRRARRTKRHRSTPH |
| Specificity |
This antibody is predicted to not cross-react with other members of the LRFN family. |
| Isotype |
IgG |
| Clonality |
Polyclonal |
| Host |
Rabbit |
| Gene |
LRFN1 |
| Purity |
Peptide affinity purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- ELISA 1:100-1:2000
- Immunocytochemistry/ Immunofluorescence 20 ug/ml
- Immunohistochemistry 2.5 ug/ml
- Immunohistochemistry-Paraffin 2.5 ug/ml
- Western Blot 1-2 ug/ml
|
| Control Peptide |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
PBS |
| Preservative |
0.02% Sodium Azide |
| Concentration |
1 mg/ml |
| Purity |
Peptide affinity purified |
Alternate Names for SALM2/LRFN1 Antibody - BSA Free
Background
LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist. This antibody is predicted to not cross-react with other members of the LRFN family.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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