RSK4 Antibody (374521) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB
• Clone: 374521
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 488

RSK4 Antibody (374521) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human RSK4
  Met1-Leu745
  Accession # Q9UK32
• Specificity: Detects human RSK4 in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) RSK1, rhRSK2, or rhRSK3 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for RSK4 Antibody (374521) [Alexa Fluor® 488]

• EC 2.7.11
• EC 2.7.11.1
• p90-RSK 6
• p90RSK6
• pp90RSK4
• PP90RSK4,90 kDa ribosomal protein S6 kinase 6
• ribosomal protein S6 kinase alpha-6
• ribosomal protein S6 kinase, 90kDa, polypeptide 6
• Ribosomal S6 kinase 4
• RPS6KA6
• RSK4
• RSK-4
• RSK4ribosomal protein S6 kinase, 90kD, polypeptide 6
• S6K-alpha 6
• S6K-alpha-6

Background

The 90 kDa ribosomal protein S6 kinases (RSK1-4) are a family of broadly expressed Ser/Thr kinases frequently activated in response to mitogenic stimuli, including growth factors and tumor-promoting phorbol esters. RSK4, also known as RPS6KA6, is commonly deleted in patients with complex X-linked mental retardation. Unlike other RSKs, RSK4 is constitutively active in serum-starved cells, and may participate in non-growth factor signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.