RPL10 Antibody (OTI6B11) [mFluor Violet 500 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI6B11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

RPL10 Antibody (OTI6B11) [mFluor Violet 500 SE] Summary

• Immunogen: Full length human recombinant protein of human RPL10 (NP_006004) produced in E.coli.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: RPL10
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for RPL10 Antibody (OTI6B11) [mFluor Violet 500 SE]

• 60S ribosomal protein L10
• DXS648EFLJ27072
• DXS648FLJ23544
• Laminin receptor homolog
• NOV
• Protein QM
• QMDKFZp686J1851
• ribosomal protein L10
• Tumor suppressor QM
• Wilms tumor-related protein

Background

The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, while Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. A distant member of the MAP kinase family, designated c-Jun NH2-terminal kinase (JNK1) functions to regulate c-Jun by phosphorylation at the amino terminal serine regulatory sites, Ser 63 and Ser 73). QM has been described as a transcription factor that can function to bind DNA directly or alternatively can interact with c-Jun to inhibit transactivation of AP-1 promoter driven reporter vectors by Jun-Jun homodimers. QM is highly conserved throughout eukaryotic evolution and is apparently a member of a multi-gene family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RPL10