RhoB Antibody [DyLight 550]

Product Discontinued

RhoB Antibody [DyLight 550] Summary

• Immunogen: ras homolog gene family, member B. (Uniprot# P62745)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RHOB
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for RhoB Antibody [DyLight 550]

• ARH6MSTP081
• ARHBAplysia RAS-related homolog 6
• h6
• MST081
• oncogene RHO H6
• ras homolog gene family, member B
• Rho cDNA clone 6
• RHOH6RhoB
• rho-related GTP-binding protein RhoB

Background

Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RHOB