Reg1A Antibody (431202) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Clone: 431202
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 647

Reg1A Antibody (431202) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human Reg1A in Western blots. Shows 5% cross-reactivity with recombinant human (rh) Reg1B and no cross-reactivity with rhReg3A, recombinant mouse Reg1, or recombinant rat Reg1.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Reg1A Antibody (431202) [Alexa Fluor™ Plus 647]

• ICRF
• Islet cells regeneration factor
• Islet of Langerhans regenerating protein
• lithostathine-1-alpha
• P19
• pancreatic stone protein, secretory
• Pancreatic thread protein
• protein-X
• PSP
• PSPS
• PSPS1
• PTP
• REG
• Reg1A
• REG-1-alpha
• Regenerating islet-derived protein 1-alpha
• Regenerating protein I alpha

Background

Reg1A, also known as PTP, PSP, and lithostathine, is a member of the Reg family of secreted proteins with a C-type lectin domain. Due to variable glycosylation, pancreatic Reg1A exists as multiple species of 16‑18 kDa. Reg1A promotes the maintenance and growth of pancreatic islet beta -cells and intestinal villi. It is up‑regulated in pancreatitis and some carcinomas. Reg1A is an antigenic target in autoimmune diabetes. Human Reg1A shares 65%‑68% aa sequence identity with mouse and rat Reg1A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.