Reg1A Antibody (1A4)

Immunocytochemistry/Immunofluorescence: Reg1 Antibody (1A4) [NBP1-51570] - Confocal immunofluorescence analysis of PC12 cells using REG1A mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

Immunohistochemistry-Paraffin: Reg1 Antibody (1A4) [NBP1-51570] - Immunohistochemical analysis of paraffin-embedded human Pancreas tissues using REG1A mouse mAb.

Product Discontinued

Reg1A Antibody (1A4) Summary

• Immunogen: Purified recombinant fragment of human REG1A fused with hIgGFc tag expressed in HEK293 cell line.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: REG1A
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Immunocytochemistry/ Immunofluorescence 1:200-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:1000
• Theoretical MW: 19 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: 0.03% Sodium Azide
• Purity: Unpurified

Alternate Names for Reg1A Antibody (1A4)

• ICRF
• Islet cells regeneration factor
• Islet of Langerhans regenerating protein
• lithostathine-1-alpha
• P19
• pancreatic stone protein, secretory
• Pancreatic thread protein
• protein-X
• PSP
• PSPS
• PSPS1
• PTP
• REG
• Reg1A
• REG-1-alpha
• Regenerating islet-derived protein 1-alpha
• Regenerating protein I alpha

Background

This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: REG1A